I would try throwing out, but not emptying the trash. That has worked for me, if it worked without the file in place, I would empty. If not, I would put it back.
With earlier systems, I threw out almost all the preferences in my once a month cleaning proceedure which RHP developed.
The old system tended to get corrupted preference files pretty easily, but if I am not mistaken, OS X bulds new pref file every time you re-start???
HTH