This article is about using Wii for physical therapy. But there are side benefits for mental health.
I was just reading an article on the latter this morning. Not much in the way of scientific studies, but the evidence is mounting that "brain exercise" is more beneficial than was previously thought. Among the things to check out if you're interested:
positscience
mindfit
brtainage
bigbrainacademy
mybraintrainer
radicagames
(all of which are ".com"s)
Of the two software programs (first two) one is called "PC software" in the article the other doesn't say that, but I suspect it's not for a Mac. But maybe there will be some one day...