Right now my main OSX utilities are DiskWarrior 3 and MacJanitor. I run MacJanitor to do what it does
cron Scripts, cleaning out the stuff that need it, etc. and then I run Permissions and DiskWarrior for rebuilding the directory if it needs it. I have cocktail but haven't used it for a long time...I really like the way MacJanitor works.
I wish someone would come out with a reliable defragmentation program! I heard Drive 10 works but i haven't bought it and things are changing so fast with the different flavors of OSX
that....well I just wish there was a good defrag utility. I was figuring that maybe Alsoft would come out with an OSX version of PlusOptimizer, but it doesn't look like it. They sure did a heck of a job with DW 3.