Normally, it makes absolutely no difference how many chips are on the board. The only time this matters is with certain older computers--beige G3 systems, Blue and White G3s, and so on, which can not use what's called "high density" RAM.
High density RAM is RAM made with fewer chips. For example, some 256MB DIMMs have 4 chips, some have 8. DIMMs with 4 chips won't work in older computers; the computer will only "see" 128MB.
With modern computers, it doesn't matter at all.